A short enantioselective synthesis of protected L-3-hydroxy-4-methoxy-5-methyl phenylalanine and its corresponding aldehyde - A common subunit of ecteinascidin-743, safracin and congeners

被引：21

作者：

De Paolis, M ^{[1
]}

Chen, XC ^{[1
]}

Zhu, JP ^{[1
]}

机构：

[1] CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

来源：

SYNLETT | 2004年 / 04期

关键词：

amino acid; Ecteinascidin; 743; phase transfer catalyst; glycine template; L-DOPA derivative;

D O I：

10.1055/s-2004-817763

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An asymmetric synthesis of appropriately protected L-3-hydroxy-4-methoxy-5-methyl phenylalanine from 3-methyl-catechol is described featuring a key enantioselective alkylation step.

引用

页码：729 / 731

页数：3

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