Engineering secondary metabolite production in plants

被引：221

作者：

Verpoorte, R ^{[1
]}

Memelink, J

机构：

[1] Leiden Univ, Leiden Amsterdam Ctr Drug Res, Div Pharmacognosy, Leiden, Netherlands

[2] Leiden Univ, Inst Mol Plant Sci, Leiden, Netherlands

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2002年 / 13卷 / 02期

关键词：

D O I：

10.1016/S0958-1669(02)00308-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent achievements have been made in the metabolic engineering of plant secondary metabolism. Various pathways have been altered using genes encoding biosynthetic enzymes or genes encoding regulatory proteins. In addition, antisense genes have been used to block competitive pathways, thereby increasing the flux towards the desired secondary metabolites.

引用

页码：181 / 187

页数：7

共 58 条

[11] Flavonoids and isoflavonoids - a gold mine for metabolic engineering [J].

Dixon, RA ;

Steele, CL .

TRENDS IN PLANT SCIENCE, 1999, 4 (10) :394-400

[12] Alkaloid biosynthesis in plants: Biochemistry, cell biology, molecular regulation, and metabolic engineering applications [J].

Facchini, PJ .

ANNUAL REVIEW OF PLANT PHYSIOLOGY AND PLANT MOLECULAR BIOLOGY, 2001, 52 :29-66

[13] Plant aromatic L-amino acid decarboxylases: evolution, biochemistry, regulation, and metabolic engineering applications [J].

Facchini, PJ ;

Huber-Allanach, KL ;

Tari, LW .

PHYTOCHEMISTRY, 2000, 54 (02) :121-138

[14] Metabolic engineering and applications of flavonoids [J].

Forkmann, G ;

Martens, S .

CURRENT OPINION IN BIOTECHNOLOGY, 2001, 12 (02) :155-160

[15] Evaluation of transgenic tomato plants expressing an additional phytoene synthase in a fruit-specific manner [J].

Fraser, PD ;

Romer, S ;

Shipton, CA ;

Mills, PB ;

Kiano, JW ;

Misawa, N ;

Drake, RG ;

Schuch, W ;

Bramley, PM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (02) :1092-1097

[16] Combinatorial biochemistry in plants:: the case of O-methyltransferases [J].

Frick, S ;

Ounaroon, A ;

Kutchan, TM .

PHYTOCHEMISTRY, 2001, 56 (01) :1-4

[17] Development of transgenic rice plants expressing maize anthocyanin genes and increased blast resistance [J].

Gandikota, M ;

de Kochko, A ;

Chen, L ;

Ithal, N ;

Fauquet, C ;

Reddy, AR .

MOLECULAR BREEDING, 2001, 7 (01) :73-83

[18] Metabolic engineering of plant carotenoids [J].

Giuliano, G ;

Aquilani, R ;

Dharmapuri, S .

TRENDS IN PLANT SCIENCE, 2000, 5 (10) :406-409

[19] Engineering secondary metabolism in maize cells by ectopic expression of transcription factors [J].

Grotewold, E ;

Chamberlin, M ;

Snook, M ;

Siame, B ;

Butler, L ;

Swenson, J ;

Maddock, S ;

Clair, GS ;

Bowen, B .

PLANT CELL, 1998, 10 (05) :721-740

[20] Suspension cultured transgenic cells of Nicotiana tabacum expressing tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus produce strictosidine upon secologanin feeding [J].

Hallard, D ;

vanderHeijden, R ;

Verpoorte, R ;

Cardoso, MIL ;

Pasquali, G ;

Memelink, J ;

Hoge, JHC .

PLANT CELL REPORTS, 1997, 17 (01) :50-54

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