A rational nomenclature for naming peptide toxins from spiders and other venomous animals

被引：253

作者：

King, Glenn F. ^{[1
]}

Gentz, Margaret C. ^{[1
]}

Escoubas, Pierre ^{[2
]}

Nicholson, Graham M. ^{[3
]}

机构：

[1] Univ Queensland, Inst Mol Biosci, St Lucia, Qld 4072, Australia

[2] CNRS, Inst Pharmacol Mol & Cellulaire, F-06560 Valbonne, France

[3] Univ Technol Sydney, Dept Med & Mol Biosci, Broadway, NSW 2007, Australia

来源：

TOXICON | 2008年 / 52卷 / 02期

基金：

澳大利亚研究理事会;

关键词：

peptide toxin; nomenclature; spider; scorpion; cone snail; sea anemone; snake;

D O I：

10.1016/j.toxicon.2008.05.020

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Molecular toxinology research was initially driven by an interest in the small subset of animal toxins that are lethal to humans. However, the realization that many venomous creatures possess a complex repertoire of bioactive peptide toxins with potential pharmaceutical and agrochemical applications has led to an explosion in the number of new epeptide toxins being discovered and characterized. Unfortunately, this increased awareness of peptide-toxin diversity has not been matched by the development of a generic nomenclature that enables these toxins to be rationally classified, catalogued, and compared. In this article, we introduce a rational nomenclature that can be applied to the naming of peptide toxins from spiders and other venomous animals. Crown Copyright (C) 2008 Published by Elsevier Ltd. All rights reserved.

引用

页码：264 / 276

页数：13

共 112 条

[1] A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new α-KTX subfamily [J].

Abdel-Mottaleb, Y ;

Coronas, FV ;

de Roodt, AR ;

Possani, LD ;

Tytgat, J .

FEBS LETTERS, 2006, 580 (02) :592-596

[2] TOXITYPING RAT-BRAIN CALCIUM CHANNELS WITH OMEGA-TOXINS FROM SPIDER AND CONE SNAIL VENOMS [J].

ADAMS, ME ;

MYERS, RA ;

IMPERIAL, JS ;

OLIVERA, BM .

BIOCHEMISTRY, 1993, 32 (47) :12566-12570

[3] Agatoxins:: ion channel specific toxins from the American funnel web spider, Agelenopsis aperta [J].

Adams, ME .

TOXICON, 2004, 43 (05) :509-525

[4] Guide to Receptors and Channels, 2nd edition (2007 Revision) [J].

Alexander, Stephen P. H. ;

Mathie, Alistair ;

Peters, John A. .

BRITISH JOURNAL OF PHARMACOLOGY, 2007, 150 :S1-S168

[5] CHARACTERIZATION AND LOCALIZATION OF A NOVEL NEURORECEPTOR FOR THE PEPTIDE SARAFOTOXIN [J].

AMBAR, I ;

KLOOG, Y ;

KOCHVA, E ;

WOLLBERG, Z ;

BDOLAH, A ;

ORON, U ;

SOKOLOVSKY, M .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1988, 157 (03) :1104-1110

[6] Cytolytic peptide and protein toxins from sea anemones (Anthozoa: Actiniaria) [J].

Anderluh, G ;

Macek, P .

TOXICON, 2002, 40 (02) :111-124

[7] α-selenoconotoxins, a new class of potent α7 neuronal nicotinic receptor antagonists [J].

Armishaw, Christopher J. ;

Daly, Norelle L. ;

Nevin, Simon T. ;

Adams, David J. ;

Craik, David J. ;

Alewood, Paul F. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (20) :14136-14143

[8] OMEGA-AGA-I - A PRESYNAPTIC CALCIUM-CHANNEL ANTAGONIST FROM VENOM OF THE FUNNEL WEB SPIDER, AGELENOPSIS-APERTA [J].

BINDOKAS, VP ;

ADAMS, ME .

JOURNAL OF NEUROBIOLOGY, 1989, 20 (04) :171-188

[9] The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003 [J].

Boeckmann, B ;

Bairoch, A ;

Apweiler, R ;

Blatter, MC ;

Estreicher, A ;

Gasteiger, E ;

Martin, MJ ;

Michoud, K ;

O'Donovan, C ;

Phan, I ;

Pilbout, S ;

Schneider, M .

NUCLEIC ACIDS RESEARCH, 2003, 31 (01) :365-370

[10] Sea anemone venom as a source of insecticidal peptides acting on voltage-gated Na+ channels [J].

Bosmans, Frank ;

Tytgat, Jan .

TOXICON, 2007, 49 (04) :550-560

← 1 2 3 4 5 6 7 8 9 10 →