Recognizing phosphatidylinositol 3-phosphate

被引：79

作者：

Misra, S ^{[1
]}

Miller, GJ ^{[1
]}

Hurley, JH ^{[1
]}

机构：

[1] NIDDKD, Mol Biol Lab, NIH, Bethesda, MD 20892 USA

来源：

CELL | 2001年 / 107卷 / 05期

关键词：

D O I：

10.1016/S0092-8674(01)00594-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Phosphatidylinositol 3-phosphate directs the endosomal localization of regulatory proteins by binding to FYVE and PX domains. New structures of these domains complexed with the phosphoinositide headgroup show how interactions with phosphate and hydroxyl groups differentiate this lipid from all others.

引用

收藏

页码：559 / 562

页数：4

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