An optical biosensor for rapid and label-free detection of cells

被引：47

作者：

Acharya, G

Chang, CL

Savran, C ^{[1
]}

机构：

[1] Purdue Univ, Sch Mech Engn, W Lafayette, IN 47907 USA

[2] Purdue Univ, Sch Elect & Comp Engn, W Lafayette, IN 47907 USA

[3] Purdue Univ, Birck Nanotechnol Ctr, W Lafayette, IN 47907 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 12期

关键词：

D O I：

10.1021/ja057490l

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a broadly applicable optical method for rapid and label-free detection of as few as 45 cells. In this method, bacterial cells are detected by measuring the amount of laser light transmitted through a small glass well functionalized with antibodies which specifically recognize and capture the cells. The described approach is simple, rapid, economical, and promising for portable and high-throughput detection of a wide variety of pathogenic and infectious cells. Copyright © 2006 American Chemical Society.

引用

页码：3862 / 3863

页数：2

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