Antimicrobial constituents from the stem bark of Feronia limonia

被引：56

作者：

Rahman, MM ^{[1
]}

Gray, AI ^{[1
]}

机构：

[1] Univ Strathclyde, Dept Pharmaceut Sci, Glasgow G4 0NR, Lanark, Scotland

来源：

PHYTOCHEMISTRY | 2002年 / 59卷 / 01期

关键词：

Feronia limonia; Rutaceae; alkaloid; coumarins; flavanones; lignan; (-)-(2S)-5,3 '-dihydroxy-4 '-methoxy-6 '',6 ''-dimethylchromeno (7,8,2 '',3 '')-flavanone; antimicrobial;

D O I：

10.1016/S0031-9422(01)00423-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The stem bark of Feronia linonia (Fain. Rutaceae) yielded (-)-(2S)-5.3'-dihydroxy-4'-methoxy-6",6"-dimethylchromeno-(7,8,2",3")-flavanone along with several known compounds including an alkaloid, five coumarins, a flavanone, a lignan, three sterols and a triterpene. The structures of these compounds were determined by spectroscopic methods, mainly 1D and 2D NMR. The antimicrobial screening of compounds by a microdilution technique resulted in MICs in the range 25-100 mug/ml. Other biological activities of the known compounds are also discussed. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：73 / 77

页数：5

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