Gd(III)-doped carbon dots as a dual fluorescent-MRI probe

被引:224
作者
Bourlinos, Athanasios B. [3 ]
Bakandritsos, Aristides [2 ]
Kouloumpis, Antonios [4 ]
Gournis, Dimitrios [4 ]
Krysmann, Marta [1 ]
Giannelis, Emmanuel P. [1 ,5 ]
Polakova, Katerina [6 ]
Safarova, Klara [6 ]
Hola, Katerina [6 ]
Zboril, Radek [6 ]
机构
[1] Cornell Univ, Ithaca, NY 14853 USA
[2] Univ Patras, Dept Mat Sci, Patras 26504, Greece
[3] Univ Ioannina, Dept Phys, GR-45110 Ioannina, Greece
[4] Univ Ioannina, Dept Mat Sci & Engn, GR-45110 Ioannina, Greece
[5] King Fahd Univ Petr & Minerals, Ctr Refining & Petrochem, Dhahran 31261, Saudi Arabia
[6] Palacky Univ, Fac Sci, Dept Phys Chem, Reg Ctr Adv Technol & Mat, Olomouc 77146, Czech Republic
关键词
MAGNETIC-RESONANCE; QUANTUM DOTS; GADOLINIUM; NANOPARTICLES; SURFACE; OXIDE;
D O I
10.1039/c2jm35592b
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070305 [高分子化学与物理];
摘要
We describe the synthesis of Gd(III)-doped carbon dots as dual fluorescence-MRI probes for biomedical applications. The derived Gd(III)-doped carbon dots show uniform particle size (3-4 nm) and gadolinium distribution and form stable dispersions in water. More importantly, they exhibit bright fluorescence, strong T1-weighted MRI contrast and low cytotoxicity.
引用
收藏
页码:23327 / 23330
页数:4
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