Complexation of several benzimidazole-type fungicides with α- and β-cyclodextrins

被引：122

作者：

Lezcano, M

Al-Soufi, W ^{[1
]}

Novo, M

Rodríguez-Núñez, E

Tato, JV

机构：

[1] Univ Santiago de Compostela, Fac Ciencias, Dept Quim Fis & Fis Aplicada, E-27002 Lugo, Spain

[2] Univ Cent Marta Abreu Villas, Dept Quim, Santa Clara, Cuba

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2002年 / 50卷 / 01期

关键词：

cyclodextrins; fungicides; inclusion complexes; principal components analysis;

D O I：

10.1021/jf010927y

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

The potential increase in water solubility of three benzimidazole-type fungicides (thiabendazole, carbendazim, and fuberidazole) due to complexation with alpha- and beta-cyclodextrins was investigated. Fluorescence emission spectra of the fungicides in the presence of different concentrations of the cyclodextrins were measured. Analysis of these spectra by the method of principal components global analysis (PCGA) yielded precise values for the association constants and the emission spectra of the fungicide-cyclodextrin inclusion complexes. Phase-solubility diagrams confirmed the formation of inclusion complexes between each of the fungicides and beta-cyclodextrin and showed significant increases of their solubilities due to complexation.

引用

页码：108 / 112

页数：5

共 13 条

[1] Principal component global analysis of fluorescence and absorption spectra of 2-(2′-hydroxyphenyl)benzimidazole [J].