Obesity and type 2 diabetes mellitus: A treatment challenge

被引：4

作者：

Gumbiner, B ^{[1
]}

Battiwalla, M ^{[1
]}

机构：

[1] Merck & Co Inc, Merck Res Labs, Clin Res Endocrinol & Metab, Rahway, NJ 07065 USA

来源：

ENDOCRINOLOGIST | 2002年 / 12卷 / 01期

关键词：

D O I：

10.1097/00019616-200201000-00007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This article discusses the pathophysiologic relationship between type 2 diabetes mellitus and obesity and the effect of obesity on the complications of that disease. It is concluded that obesity plays an important role in type 2 diabetes and that modulating body weight can be an important therapeutic modality in treating this illness.

引用

页码：23 / 28

页数：6

共 61 条

[1] Amer Diabet Assoc, 1998, DIABETES CARE, V21, P2180
[2] [Anonymous], 2000, Pediatrics, V105, P671
[3] [Anonymous], NIH PUBL
[4] HEMODYNAMIC ACTIONS OF INSULIN
BARON, AD
[J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1994, 267 (02): : E187 - E202
[5] METABOLIC IMPLICATIONS OF BODY-FAT DISTRIBUTION
BJORNTORP, P
[J]. DIABETES CARE, 1991, 14 (12) : 1132 - 1143
[6] OBESITY, FAT DISTRIBUTION, AND WEIGHT-GAIN AS RISK-FACTORS FOR CLINICAL DIABETES IN MEN
CHAN, JM
RIMM, EB
COLDITZ, GA
STAMPFER, MJ
WILLETT, WC
[J]. DIABETES CARE, 1994, 17 (09) : 961 - 969
[7] CONTRIBUTION OF OBESITY TO DEFECTS OF INTRACELLULAR GLUCOSE-METABOLISM IN NIDDM
CHUNG, JW
SUH, KI
JOYCE, M
DITZLER, T
HENRY, RR
[J]. DIABETES CARE, 1995, 18 (05) : 666 - 673
[8] WEIGHT-GAIN AS A RISK FACTOR FOR CLINICAL DIABETES-MELLITUS IN WOMEN
COLDITZ, GA
WILLETT, WC
ROTNITZKY, A
MANSON, JE
[J]. ANNALS OF INTERNAL MEDICINE, 1995, 122 (07) : 481 - 486
[9] COLDITZ GA, 1999, AM J EPIDEMIOL, V312, P501
[10] THE TRIUMVIRATE - BETA-CELL, MUSCLE, LIVER - A COLLUSION RESPONSIBLE FOR NIDDM
DEFRONZO, RA
[J]. DIABETES, 1988, 37 (06) : 667 - 687

← 1 2 3 4 5 6 7 →