Amyotrophic lateral sclerosis: From disease mechanisms to therapies

被引:15
作者
Bruijn, LI [1 ]
机构
[1] Amyotroph Lateral Sclerosis Assoc, Off Sci Director, Guilford, CT 06437 USA
关键词
D O I
10.2144/02325dd01
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:1112 / +
页数:6
相关论文
共 67 条
[31]   FINE-STRUCTURAL OBSERVATIONS OF NEUROFILAMENTOUS CHANGES IN AMYOTROPHIC LATERAL SCLEROSIS [J].
HIRANO, A ;
DONNENFELD, H ;
SASAKI, S ;
NAKANO, I .
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1984, 43 (05) :461-470
[32]   FINE-STRUCTURAL STUDY OF NEUROFIBRILLARY CHANGES IN A FAMILY WITH AMYOTROPHIC LATERAL SCLEROSIS [J].
HIRANO, A ;
NAKANO, I ;
KURLAND, LT ;
MULDER, DW ;
HOLLEY, PW ;
SACCOMANNO, G .
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1984, 43 (05) :471-480
[33]   Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus [J].
Hottinger, AF ;
Azzouz, M ;
Déglon, N ;
Aebischer, P ;
Zurn, AD .
JOURNAL OF NEUROSCIENCE, 2000, 20 (15) :5587-5593
[34]   The copper chelator d-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis [J].
Hottinger, AF ;
Fine, EG ;
Gurney, ME ;
Zurn, AD ;
Aebischer, P .
EUROPEAN JOURNAL OF NEUROSCIENCE, 1997, 9 (07) :1548-1551
[35]   Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS) [J].
Howland, DS ;
Liu, J ;
She, YJ ;
Goad, B ;
Maragakis, NJ ;
Kim, B ;
Erickson, J ;
Kulik, J ;
DeVito, L ;
Psaltis, G ;
DeGennaro, LJ ;
Cleveland, DW ;
Rothstein, JD .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (03) :1604-1609
[36]   Transgenic mice expressing Alzheimer amyloid precursor proteins [J].
Hsiao, K .
EXPERIMENTAL GERONTOLOGY, 1998, 33 (7-8) :883-889
[37]   Novel drug development for amyotrophic lateral sclerosis [J].
Hurko, O ;
Walsh, FS .
JOURNAL OF THE NEUROLOGICAL SCIENCES, 2000, 180 (1-2) :21-28
[38]   Formation of high molecular weight complexes of mutant Cu,Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis [J].
Johnston, JA ;
Dalton, MJ ;
Gurney, ME ;
Kopito, RR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (23) :12571-12576
[39]   Amyotrophic lateral sclerosis: Unfolding the toxicity of the misfolded [J].
Julien, JP .
CELL, 2001, 104 (04) :581-591
[40]   Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis [J].
Klivenyi, P ;
Ferrante, RJ ;
Matthews, RT ;
Bogdanov, MB ;
Klein, AM ;
Andreassen, OA ;
Mueller, G ;
Wermer, M ;
Kaddurah-Daouk, R ;
Beal, MF .
NATURE MEDICINE, 1999, 5 (03) :347-350