Capacity of Helicobacter pylori to generate ionic gradients at low pH is similar to that of bacteria which grow under strongly acidic conditions

被引：26

作者：

Matin, A

Zychlinsky, E

Keyhan, M

Sachs, G

机构：

来源：

INFECTION AND IMMUNITY | 1996年 / 64卷 / 04期

关键词：

D O I：

10.1128/IAI.64.4.1434-1436.1996

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Helicobacter pylori colonizes the highly acidic human gastric mucosa. At pH 3.0 to 7.0, this bacterium maintained a nearly neutral internal pH. Its membrane potential changed reciprocally with the pH gradient so that a relatively constant proton motive force was maintained. Possibly, the capacity to maintain an appropriate transmembrane ionic gradient al a low pH contributes to the pathogenic propensities of this bacterium.

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页码：1434 / 1436

页数：3

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