Peptidomimetics and Peptide Backbone Modifications

被引：98

作者：

Ahn, Jung-Mo ^{[1
]}

Boyle, Nicholas A. ^{[1
]}

MacDonald, Mary T. ^{[1
]}

Janda, Kim D. ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2002年 / 2卷 / 05期

关键词：

D O I：

10.2174/1389557023405828

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The replacement of the amide bond in a peptide backbone is a widely used form of peptide mimicry. Several of the most common amide bond surrogates, including peptidomimetic work done in this laboratory, and their biological applications are presented in this review.

引用

页码：463 / 473

页数：11

共 112 条

[1] A THEORETICAL AND CRYSTALLOGRAPHIC STUDY OF THE GEOMETRIES AND CONFORMATIONS OF FLUOROOLEFINS AS PEPTIDE ANALOGS
ABRAHAM, RJ
ELLISON, SLR
SCHONHOLZER, P
THOMAS, WA
[J]. TETRAHEDRON, 1986, 42 (07) : 2101 - 2110
[2] FLUOROOLEFIN DIPEPTIDE ISOSTERES .1. THE SYNTHESIS OF GLY-PSI(CF=CH)GLY AND RACEMIC PHE-PSI(CF=CH)GLY
ALLMENDINGER, T
FURET, P
HUNGERBUHLER, E
[J]. TETRAHEDRON LETTERS, 1990, 31 (50) : 7297 - 7300
[3] Anderson G J, 1997, Methods Mol Biol, V73, P49
[4] Aube J, 1997, ADV AMIN AC MIM PEPT, V1, P193
[5] PSEUDOPEPTIDES AND BETA-FOLDING - X-RAY STRUCTURES COMPARED WITH STRUCTURES IN SOLUTION
AUBRY, A
MARRAUD, M
[J]. BIOPOLYMERS, 1989, 28 (01) : 109 - 122
[6] Barker A.A., 1974, BIOCHEM J, V139, P555
[7] PHOSPHINIC ACID DIPEPTIDE ANALOGS - POTENT, SLOW-BINDING INHIBITORS OF ASPARTIC PEPTIDASES
BARTLETT, PA
KEZER, WB
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (15) : 4282 - 4283
[8] EVALUATION OF INTRINSIC BINDING-ENERGY FROM A HYDROGEN-BONDING GROUP IN AN ENZYME-INHIBITOR
BARTLETT, PA
MARLOWE, CK
[J]. SCIENCE, 1987, 235 (4788) : 569 - 571
[9] PHOSPHONAMIDATES AS TRANSITION-STATE ANALOG INHIBITORS OF THERMOLYSIN
BARTLETT, PA
MARLOWE, CK
[J]. BIOCHEMISTRY, 1983, 22 (20) : 4618 - 4624
[10] POTENT INHIBITION OF PEPSIN AND PENICILLOPEPSIN BY PHOSPHORUS-CONTAINING PEPTIDE ANALOGS
BARTLETT, PA
HANSON, JE
GIANNOUSIS, PP
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (26) : 6268 - 6274

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