Chemistry - Seamless proteins tie up their loose ends

被引：247

作者：

Craik, DJ ^{[1
]}

机构：

[1] Univ Queensland, Inst Mol Biosci, Brisbane, Qld 4072, Australia

来源：

SCIENCE | 2006年 / 311卷 / 5767期

关键词：

D O I：

10.1126/science.1125248

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Natural circular proteins found in bacteria, plants, and mammals show antimicrobial activity and exceptional stability, making them ideal templates for engineering better drugs. But just how they close into loops remains a mystery.

引用

页码：1563 / 1564

页数：2

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