Ion-pair liquid chromatographic determination of albendazole in cattle feed

被引：6

作者：

Botsoglou, NA ^{[1
]}

Fletouris, DJ ^{[1
]}

Psomas, IE ^{[1
]}

机构：

[1] Aristotelian Univ Salonika, Sch Vet Med, GR-54006 Salonika, Greece

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 1999年 / 22卷 / 15期

关键词：

D O I：

10.1081/JLC-100101802

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A liquid chromatographic method is described for the determination of albendazole in cattle feeds. Samples are extracted with acetonitrile, and the extracts, after partitioning with hexane, are analyzed by ion-pair liquid chromatography with detection at 292 nm. Albendazole is eluted from the column well resolved from its oxidation byproducts. The method shows analytical characteristics well within acceptable limits. Recovery was in the range of 98.2-100.4%, while precision, expressed as percent relative standard deviation, in the range of 1.6-3.1%. Limit of detection was estimated at 0.5 mu g/g, and limit of determination at 1.0 mu g/g.

引用

页码：2297 / 2305

页数：9

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