Existence of Na+-translocating NADH-quinone reductase in Haemophilus influenzae

被引：41

作者：

Hayashi, M ^{[1
]}

Nakayama, Y ^{[1
]}

Unemoto, T ^{[1
]}

机构：

[1] CHIBA UNIV,FAC PHARMACEUT SCI,LAB MEMBRANE BIOCHEM,INAGE KU,CHIBA 263,JAPAN

来源：

FEBS LETTERS | 1996年 / 381卷 / 03期

关键词：

Na+ pump; Na+-translocating NADH-quinone reductase; Haemophilus influenzae; nqr Operon; complex I; Vibrio alginolyticus;

D O I：

10.1016/0014-5793(96)00114-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We previously cloned and sequenced nqr operon encoding the Na+-translocating NADH-quinone reductase (NQR) from the marine bacterium Vibrio alginolyticus. A gene cluster very similar to nqr operon was found to exist in the genome of Haemophilus influenzae Rd. We examined the membrane fraction from H. influenzae, and the respiratory chain of H. influenzae was found to contain a Na+-dependent NQR that is essentially identical to those found in the marine V. alginoltyticus. These results indicate that quite similar to the salt-loving marine bacteria, the blood-loving H. influenzae has a redox-driven Na+ pump and utilizes Na+ circulation for energy coupling.

引用

页码：174 / 176

页数：3

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