The serotonin 5-HT2B receptor from the puffer fish Tetraodon fluviatilis:: cDNA cloning, genomic organization and alternatively spliced variants

被引：17

作者：

De Lucchini, S

Marracci, S

Nardi, I

机构：

[1] Univ Pisa, Dipartimento Fisiol & Biochim, Lab Biol Cellulare & Sviluppo, I-56010 Pisa, Italy

[2] Scuola Normale Super Pisa, I-56100 Pisa, Italy

来源：

MOLECULAR BRAIN RESEARCH | 2001年 / 97卷 / 01期

关键词：

5-HT2B receptor; serotonin receptor; Tetraodon; genomic organization; splice variant; alternative splicing;

D O I：

10.1016/S0169-328X(01)00293-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We cloned the 5-HT2B serotonin receptor from the puffer fish Tetraodon fluviatilis. Two cDNAs differing in length because of the use of alternative polyadenylation sites were isolated. We partly characterized the genomic organization of the 5-HT2B gene and we found two introns conserved in position between the puffer fish and mammals. In addition, four splice variants which would generate truncated forms of the receptor were detected. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：89 / 93

页数：5

共 23 条

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