exo-glycal approaches to C-linked glycosyl amino acid synthesis

被引：60

作者：

Campbell, AD

Paterson, DE

Raynham, TM

Taylor, RJK ^{[1
]}

机构：

[1] Univ York, Dept Chem, York YO10 5DD, N Yorkshire, England

[2] Roche Discovery Welwyn, Welwyn Garden City AL7 3AY, Herts, England

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 16期

关键词：

D O I：

10.1039/a905014k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Two novel routes to C-linked glycosyl amino acids are described; the first involves elaboration of an exo-glycal and subsequent Ramberg-Backlund rearrangement of a sulfone intermediate to give, after functional group manipulation, a protected C-glycosyl serine, while the second uses hydroboration-Suzuki coupling of the same exo-glycal to produce ultimately the corresponding C-glycosyl asparagine analogue.

引用

页码：1599 / 1600

页数：2

共 19 条

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