X-ray microfocussing combined with microfluidics for on-chip X-ray scattering measurements

被引:64
作者
Barrett, R
Faucon, M
Lopez, J
Cristobal, G
Destremaut, F
Dodge, A
Guillot, P
Laval, P
Masselon, C
Salmon, JB
机构
[1] CNRS Rhodia, Unite Mixte, Lab Futur, F-33600 Pessac, France
[2] European Synchrotron Radiat Facil, F-38043 Grenoble, France
[3] Univ Bordeaux 1, CEA, CNRS, UMR 5107,CELIA,Grp PALA, F-33405 Talence, France
关键词
D O I
10.1039/b517055a
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This work describes the fabrication of thin microfluidic devices in Kapton ( polyimide). These chips are well-suited to perform X-ray scattering experiments using intense microfocussed beams, as Kapton is both relatively resistant to the high intensities generated by a synchrotron, and almost transparent to X-rays. We show networks of microchannels obtained using laser ablation of Kapton films, and we also present a simple way to perform fusion bonding between two Kapton films. The possibilities offered using such devices are illustrated with X-ray scattering experiments. These experiments demonstrate that structural measurements in the 1 angstrom-20 nm range can be obtained with spatial resolutions of a few microns in a microchannel.
引用
收藏
页码:494 / 499
页数:6
相关论文
共 43 条
[21]   Time-resolved resonance Raman analysis of chromophore structural changes in the formation and decay of rhodopsin's BSI intermediate [J].
Pan, DH ;
Ganim, Z ;
Kim, JE ;
Verhoeven, MA ;
Lugtenburg, J ;
Mathies, RA .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (17) :4857-4864
[22]   Compactness of the denatured state of a fast-folding protein measured by submillisecond small-angle x-ray scattering [J].
Pollack, L ;
Tate, MW ;
Darnton, NC ;
Knight, JB ;
Gruner, SM ;
Eaton, WA ;
Austin, RH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (18) :10115-10117
[23]   Time resolved collapse of a folding protein observed with small angle x-ray scattering [J].
Pollack, L ;
Tate, MW ;
Finnefrock, AC ;
Kalidas, C ;
Trotter, S ;
Darnton, NC ;
Lurio, L ;
Austin, RH ;
Batt, CA ;
Gruner, SM ;
Mochrie, SGJ .
PHYSICAL REVIEW LETTERS, 2001, 86 (21) :4962-4965
[24]  
PREUSS S, 1995, APPL PHYS A-MATER, V61, P33, DOI 10.1007/BF01538207
[25]  
Ricciardi G, 1998, CIRP ANNALS 1998 - MANUFACTURING TECHNOLOGY, VOL 47, NO 1, V47, P145
[26]   Performance of an integrated microoptical system for fluorescence detection in microfluidic systems [J].
Roulet, JC ;
Völkel, R ;
Herzig, HP ;
Verpoorte, E ;
de Rooij, NF ;
Dändliker, R .
ANALYTICAL CHEMISTRY, 2002, 74 (14) :3400-3407
[27]   Rapid compaction during RNA folding [J].
Russell, R ;
Millettt, IS ;
Tate, MW ;
Kwok, LW ;
Nakatani, B ;
Gruner, SM ;
Mochrie, SGJ ;
Pande, V ;
Doniach, S ;
Herschlag, D ;
Pollack, L .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (07) :4266-4271
[28]   In situ Raman imaging of interdiffusion in a microchannel -: art. no. 094106 [J].
Salmon, JB ;
Ajdari, A ;
Tabeling, P ;
Servant, L ;
Talaga, D ;
Joanicot, M .
APPLIED PHYSICS LETTERS, 2005, 86 (09) :1-3
[29]   Velocity profiles in shear-banding wormlike micelles [J].
Salmon, JB ;
Colin, A ;
Manneville, S ;
Molino, F .
PHYSICAL REVIEW LETTERS, 2003, 90 (22) :4-228303
[30]   ID18F: a new micro-x-ray fluorescence end-station at the European Synchrotron Radiation Facility (ESRF): preliminary results [J].
Somogyi, A ;
Drakopoulos, M ;
Vincze, L ;
Vekemans, B ;
Camerani, C ;
Janssens, K ;
Snigirev, A ;
Adams, F .
X-RAY SPECTROMETRY, 2001, 30 (04) :242-252