Three-dimensional optical tomographic Imaging of breast in a human subject

被引：94

作者：

Jiang, H ^{[1
]}

Xu, Y

Iftimia, N

Eggert, J

Klove, K

Baron, L

Fajardo, L

机构：

[1] Clemson Univ, Dept Phys & Astron, Biomed Opt Lab, Clemson, SC 29634 USA

[2] Greenville Gen Hosp, Breast Hlth Ctr, Greenville, SC 29605 USA

[3] Med Univ S Carolina, Dept Radiol, Charleston, SC 29425 USA

[4] Johns Hopkins Med Inst, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA

来源：

IEEE TRANSACTIONS ON MEDICAL IMAGING | 2001年 / 20卷 / 12期

关键词：

breast diffuse optical tomography; photon migration; three-dimensional image reconstruction;

D O I：

10.1109/42.974928

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

We present for the first time a full three-dimensional (3-D) reconstruction of absorption images of breast from continuous-wave (cw) measurements performed on a premenopausal woman. Our 3-D optical images clearly reveal a large primary tumor as well as a small secondary tumor in a separate location of the breast. The multiple tumors identified by our 3-D optical imaging have been confirmed by the subsequent biopsy examination of the breast. Quantitative information of the optical images obtained is provided in terms of the location, size, and absorption coefficient of the tumors.

引用

页码：1334 / 1340

页数：7

共 28 条

[1]

Arridge SR, 2000, INT J IMAG SYST TECH, V11, P2, DOI 10.1002/(SICI)1098-1098(2000)11:1<2::AID-IMA2>3.0.CO

[2]

2-J

[3] Nonuniqueness in diffusion-based optical tomography [J].

Arridge, SR ;

Lionheart, WRB .

OPTICS LETTERS, 1998, 23 (11) :882-884

[4] A fundamental limitation of linearized algorithms for diffuse optical tomography [J].

Boas, D. A. .

OPTICS EXPRESS, 1997, 1 (13) :404-413

[5] Optical tomographic image reconstruction from ultrafast time-sliced transmission measurements [J].

Cai, W ;

Gayen, SK ;

Xu, M ;

Zevallos, M ;

Alrubaiee, M ;

Lax, M ;

Alfano, RR .

APPLIED OPTICS, 1999, 38 (19) :4237-4246

[6] Clinical optical tomography and NIR spectroscopy for breast cancer detection [J].

Colak, SB ;

van der Mark, MB ;

Hooft, GW ;

Hoogenraad, JH ;

van der Linden, ES ;

Kuijpers, FA .

IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 1999, 5 (04) :1143-1158

[7] Tomographic image reconstruction from optical projections in light-diffusing media [J].

Colak, SB ;

Papaioannou, DG ;

tHooft, GW ;

vanderMark, MB ;

Schomberg, H ;

Paasschens, JCJ ;

Melissen, JBM ;

vanAsten, NAAJ .

APPLIED OPTICS, 1997, 36 (01) :180-213

[8] Three-dimensional optical tomography [J].

Eppstein, MJ ;

Dougherty, DE ;

Hawrysz, DJ ;

Sevick-Muraca, EM .

OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE III, PROCEEDINGS OF, 1999, 3597 :97-105

[9]

GRABER HL, 1993, P SOC PHOTO-OPT INS, V1888, P372, DOI 10.1117/12.154656

[10] Simultaneous reconstruction of absorption and scattering images by multichannel measurement of purely temporal data [J].

Hebden, JC ;

Schmidt, FEW ;

Fry, ME ;

Schweiger, M ;

Hillman, EMC ;

Delpy, DT ;

Arridge, SR .

OPTICS LETTERS, 1999, 24 (08) :534-536

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