The solvates of o-acetamidobenzamide

被引：21

作者：

Barnett, Sarah A. ^{[1
]}

Tocher, Derek A. ^{[1
]}

Vickers, Martin ^{[1
]}

机构：

[1] UCL, Dept Chem, London WC1H 0AJ, England

来源：

CRYSTENGCOMM | 2006年 / 8卷 / 04期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1039/b600288a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of six solvates of o-acetamidobenzamide have been prepared and characterized by single crystal X-ray diffraction. With the exception of the chloroform solvate, five of these, the 1-propanol, 1-butanol, 2-butanol, 1,2-dichloroethane, and 1,4-dioxane solvates are isostructural with similar unit cells and atomic positions for the o-acetamidobenzamide molecules. In all cases, the solvent molecules occupy pores within the hydrogen-bonded sheets of o-acetamidobenzamide. These molecules are readily lost when the crystals are exposed to the atmosphere.

引用

页码：313 / 319

页数：7

共 16 条

[1] Crystal engineering of the composition of pharmaceutical phases.: Do pharmaceutical co-crystals represent a new path to improved medicines? [J].