New sesquiterpenes from the roots of Ligularia dentata

被引：21

作者：

Gao, K

Yang, L

Jia, ZJ

机构：

[1] LANZHOU UNIV,DEPT CHEM,LANZHOU 730000,PEOPLES R CHINA

[2] LANZHOU UNIV,STATA KEY LAB APPL ORGAN CHEM,LANZHOU 730000,PEOPLES R CHINA

来源：

PLANTA MEDICA | 1997年 / 63卷 / 05期

关键词：

Ligularia dentata; Compositae; roots; sesquiterpenes; bisabolane;

D O I：

10.1055/s-2006-957734

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Phytochemical investigation of the roots of Ligularia dentata has resulted in the isolation of three new bisabolane sesquiterpenes: 1 alpha,3 beta P,10,11-tetrahydroxy-2 alpha,5 alpha,8-triangeloyloxybisabola-(7)1 4-en-4-one (1), 1 alpha,3 beta,10-trihydroxy-11-methoxy-2 alpha,5 alpha,8-triangeloyloxybisabola-7(14) (2), and 1 alpha, 3 beta,10-trihydroxy-2 alpha,5 alpha,8-triangeloyloxybisabola-7(14),11(12)-dien-4-one (3). Their structures were elucidated with spectroscopic methods and 2D-NMR techniques as well as chemical transformations. In addition, three known phenolic norsesquiterpenes, liguhodgsonal (4), ligujapone (5), and 2-hydroxyplatyphyllide (6) have also been obtained.

引用

页码：461 / 463

页数：3

共 9 条

[1]

CHEN HM, 1992, ACTA CHIM SINICA, V50, P1187

[2] SESQUITERPENES AND A DITERPENE LACTONE WITH AN UNUSUAL CARBON SKELETON FROM LIGULARIA-SAGITTA [J].

CHEN, HM ;

JIA, ZJ ;

YANG, L .

PHYTOCHEMISTRY, 1992, 31 (06) :2146-2147

[3] A HIGHLY OXYGENATED GERMACRANE FROM ASPILIA-EENII AND CONSTITUENTS FROM OTHER ASPILIA SPECIES [J].

GANZER, U ;

JAKUPOVIC, J ;

BOHLMANN, F ;

KING, RM .

PHYTOCHEMISTRY, 1992, 31 (01) :209-212

[4] GERMACRANOLIDES FROM ALLAGOPAPPUS-VISCOSISSIMUS [J].

GONZALEZ, AG ;

BARRERA, JB ;

MENDEZ, JT ;

MARTINEZ, JE ;

SANCHEZ, ML .

PHYTOCHEMISTRY, 1992, 31 (01) :330-331

[5]

HOU KC, 1982, DICT FAMILIES GENERA, P276

[6] 4 NEW FURANS FROM THE ROOTS OF LIGULARIA-PRZEWALSKII [J].

JIA, ZJ ;

ZHAO, Y .

JOURNAL OF NATURAL PRODUCTS, 1994, 57 (01) :146-150

[7] NEW SESQUITERPENES FROM THE ROOTS OF LIGULARIA-VEITCHIANA [J].

JIA, ZJ ;

ZHAO, Y ;

TAN, RX .

JOURNAL OF NATURAL PRODUCTS, 1993, 56 (04) :494-499

[8]

Jiangsu College of New Medicine, 1977, DICT TRAD CHIN MED, p[7, 154, 549, 1152, 2349]

[9] SESQUITERPENES FROM THE RHIZOMES OF LIGULARIA-DENTATA HARA [J].

NAYA, K ;

OKAYAMA, T ;

FUJIWARA, M ;

NAKATA, M ;

OHTSUKA, T ;

KURIO, S .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1990, 63 (08) :2239-2245

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