Synthesis of PI(3,4,5)P3 with unsaturated and saturated fatty acid chains

被引：17

作者：

Watanabe, Y ^{[1
]}

Nakatomi, M ^{[1
]}

机构：

[1] Ehime Univ, Fac Engn, Dept Appl Chem, Matsuyama, Ehime 7908577, Japan

来源：

TETRAHEDRON | 1999年 / 55卷 / 32期

关键词：

phosphatidyl inositol; phospholipid; natural product; protecting group;

D O I：

10.1016/S0040-4020(99)00551-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of three PI(3,4,5)P(3)s, sn-1-O-stearoyl-sn-2-O-arachidonoyl, stearoyl-linolenoyl, and distearoyl phosphatidyl-myo-inositol 3,4,5-trisphosphate with the natural configuration for the arachidonoyl version was established by employing 9-fluorenylmethyl-protected phosphate derivatives. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：9743 / 9754

页数：12

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