Use of α-chlorosulfides in indium promoted C-C couplings:: easy entry into the stereoselective formation of epoxy alkynes

被引：20

作者：

Engstrom, G ^{[1
]}

Morelli, M ^{[1
]}

Palomo, C ^{[1
]}

Mitzel, T ^{[1
]}

机构：

[1] Trinity Coll, Dept Chem, Hartford, CT 06106 USA

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 33期

关键词：

indium couplings; epoxy alkynes; stereocontrol;

D O I：

10.1016/S0040-4039(99)01152-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of alpha-chlorosulfide compounds to control stereoselectivity in indium promoted C-C couplings occurs smoothly at room temperature under aqueous and mixed aqueous/organic conditions. Use of the halide to control syn/anti ratios simplifies the indium promoted coupling with respect to earlier studies and is used to gain entry into stereocontrolled epoxy alkynes in good yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：5967 / 5970

页数：4

共 17 条

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