The double life of Irs

被引:51
作者
Haeusler, Rebecca A. [1 ]
Accili, Domenico [1 ]
机构
[1] Columbia Univ, Coll Phys & Surg, Dept Med, New York, NY 10027 USA
关键词
D O I
10.1016/j.cmet.2008.06.010
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The liver plays a central role in lipid and glucose metabolism. Two studies in this issue (Kubota et al., 2008; Dong et al., 2008) on the insulin-signaling adaptors Irs1 and Irs2 prompt a critical reappraisal of the physiology of fasting and of the integrated control of hepatic insulin action.
引用
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页码:7 / 9
页数:3
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