Curvicollides A-C:: New polyketide-derived lactones from a sclerotium-colonizing isolate of Podospora curvicolla (NRRL 25778)

被引：26

作者：

Che, YS

Gloer, JB

Wicklow, DT ^{[1
]}

机构：

[1] Univ Iowa, Dept Chem, Iowa City, IA 52242 USA

[2] USDA ARS, Natl Ctr Agr Utilizat Res, Mycotoxin Res Unit, Peoria, IL 61604 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 08期

关键词：

D O I：

10.1021/ol0498186

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

[GRAPHICS] 1 R=CH2OH R'=H 2 R=CH3 R'= OH 3 R=CH3 R'= H Curvicollides A-C (1-3) have been obtained from cultures of an isolate of Podospora curvicolla (NRRL 25778) that colonized a sclerotium of Aspergillus flavus. The structures of these compounds were elucidated by analysis of one- and two-dimensional NMR data. The lead compound (1) showed antifungal activity against A. flavus and Fusarium verticillioides.

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页码：1249 / 1252

页数：4

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