Linezolid activity compared to those of selected macrolides and other agents against aerobic and anaerobic pathogens isolated from soft tissue bite infections in humans

被引：53

作者：

Goldstein, EJC

Citron, DM

Merriam, CV

机构：

[1] Univ Calif Los Angeles, Med Ctr, RM Alden Res Lab, Santa Monica, CA 90404 USA

[2] Univ Calif Los Angeles, Sch Med, Los Angeles, CA 90024 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1999年 / 43卷 / 06期

关键词：

D O I：

10.1128/AAC.43.6.1469

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Linezolid was tested against 420 aerobes and anaerobes, including 148 Pasteurella isolates, by an agar dilution method. Linezolid was active against all Pasteurella multocida subsp. multocida and P. multocida subsp. septica isolates and most Pasteurella canis, Pasteurella dagmatis, and Pasteurella stomatis isolates. The MIC was less than or equal to 2 mu g/ml for staphylococci, streptococci, EF-4b, Weeksella zoohelcum, Fusobacterium nucleatum, other fusobacteria, Porphyromonas spp., Prevotella spp., peptostreptococci, and almost all Bacteroides tectum isolates.

引用

收藏

页码：1469 / 1474

页数：6

相关论文

共 24 条

[1] Characterization of Saccharolytic Bacteroides and Prevotella isolates from infected dog and cat bite wounds in humans [J].

Alexander, CJ ;

Citron, DM ;

Gerardo, SH ;

Claros, MC ;

Talan, D ;

Goldstein, EJC .

JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (02) :406-411

[2] MICROBIOLOGY OF HUMAN AND ANIMAL BITE WOUNDS IN CHILDREN [J].

BROOK, I .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1987, 6 (01) :29-32

[3]

CITRON DM, 1996, CLIN INFECT DIS S1, V23, P78

[4]

Dresser LD, 1998, PHARMACOTHERAPY, V18, P456

[5] In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial agents, against experimental bacterial infections [J].

Ford, CW ;

Hamel, JC ;

Wilson, DM ;

Moerman, JK ;

Stapert, D ;

Yancey, RJ ;

Hutchinson, DK ;

Barbachyn, MR ;

Brickner, SJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (06) :1508-1513

[6] BITE WOUNDS AND INFECTION [J].

GOLDSTEIN, EJC .

CLINICAL INFECTIOUS DISEASES, 1992, 14 (03) :633-638

[7]

GOLDSTEIN EJC, 1978, J CLIN MICROBIOL, V8, P667

[8] Activities of HMR 3004 (RU 64004) and HMR 3647 (RU 66647) compared to those of erythromycin, azithromycin, clarithromycin, roxithromycin, and eight other antimicrobial agents against unusual aerobic and anaerobic human and animal bite pathogens isolated from skin and soft tissue infections in humans [J].

Goldstein, EJC ;

Citron, DM ;

Gerardo, SH ;

Hudspeth, M ;

Merriam, CV .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (05) :1127-1132

[9] Trovafloxacin compared with levofloxacin, ofloxacin, ciprofloxacin, azithromycin and clarithromycin against unusual aerobic and anaerobic human and animal bite-wound pathogens [J].

Goldstein, EJC ;

Citron, DM ;

Hudspeth, M ;

Gerardo, SH ;

Merriam, CV .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1998, 41 (03) :391-396

[10]

Holdeman LV., 1977, Anaerobic laboratory manual, V4