Spectroscopic spectral-domain optical coherence microscopy

被引:75
作者
Xu, CY [1 ]
Vinegoni, C [1 ]
Ralston, TS [1 ]
Luo, W [1 ]
Tan, W [1 ]
Boppart, SA [1 ]
机构
[1] Univ Illinois, Beckman Inst Adv Sci & Technol, Biophoton Imaging Lab, Urbana, IL 61801 USA
关键词
D O I
10.1364/OL.31.001079
中图分类号
O43 [光学];
学科分类号
070207 [光学]; 0803 [光学工程];
摘要
The spectroscopic content within optical coherence tomography (OCT) data can provide a wealth of information. Spectroscopic OCT methods are frequently limited by time-frequency trade-offs that limit high spectral and spatial resolution simultaneously. We present spectroscopic spectral-domain optical coherence microscopy performed with a multimodality microscope. Restricting the spatial extent of the signal by using high-numerical-aperture optics makes high-resolution spectroscopic information accessible, facilitated with spectral-domain detection. Simultaneous acquisition of multiphoton microscopy images is used to validate tissue structure and localization of nuclei within individual cells. (c) 2006 Optical Society of America.
引用
收藏
页码:1079 / 1081
页数:3
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