Sensors for 5-hydroxytryptamine and 5-hydroxyindole acetic acid based on nanomaterial modified electrodes

被引：218

作者：

Goyal, Rajendra N. ^{[1
]}

Oyama, Munetaka ^{[2
]}

Gupta, Vinod K. ^{[1
]}

Singh, Sudhanshu P. ^{[1
]}

Sharma, Ram A. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Roorkee 247667, Uttar Pradesh, India

[2] Kyoto Univ, Grad Sch Engn, Nishikyo Ku, Kyoto 6158520, Japan

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2008年 / 134卷 / 02期

关键词：

Nanogold; Single walled carbon nanotubes; Serotonin; 5-Hydroxyindole acetic acid; Voltammetry;

D O I：

10.1016/j.snb.2008.06.027

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Simultaneous voltammetric determination of serotonin and 5-hydroxyindole acetic acid has been described at single walled carbon nanotube modified glassy carbon electrode and gold nanoparticles modified indium tin oxide electrode. The method described is fast, simple, accurate with detection limits as low as 32 nM for 5-hydroxytryptamine (5-HT) at single-walled carbon nanotube modified glassy carbon electrode and 27 nM for 5-hydroxyindole acetic acid (5-HIAA) at gold nanoparticles modified indium tin oxide electrode. Linear variation of peak current with change in concentration was observed in the concentration range 0.1 - 100 mu M for 5-HT and 5-HIAA. Application of the method for non-invasive determination of the compounds in urine samples has also been described. The inter- and intra-day stability of the electrodes were also determined and electrodes were found to be sufficiently stable for 1 week. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：816 / 821

页数：6

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