Integrated microanalytical system based on electrochemical detection and cell positioning

被引:13
作者
Castellarnau, M
Zine, N
Bausells, J
Madrid, C
Juárez, A
Samitier, J
Errachid, A
机构
[1] CREBEC, Nanobioengn Res Lab, Barcelona 08028, Spain
[2] Univ Autonoma Barcelona, Ctr Nacl Microelect, IMB, E-08193 Barcelona, Spain
来源
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS | 2006年 / 26卷 / 2-3期
关键词
dielectrophoresis; bioelectronics; pH detection; ISFET;
D O I
10.1016/j.msec.2005.10.072
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The development and preliminary evaluation of an integrated microanalytical system based on electrochemical detection and cell positioning is reported here. The chip includes ion-sensitive field effect transistors (ISFET), a single pair of castellated microelectrodes and a reference Ag/AgCl microelectrode. The ISFETs have shown good operating characteristics, with a 52 mV/pH response. Yeast cells and bacteria have been positioned on the gate region of the ISFET sensor using single pair of castellated microelectrodes. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:405 / 410
页数:6
相关论文
共 18 条
[11]   Separation of submicron bioparticles by dielectrophoresis [J].
Morgan, H ;
Hughes, MP ;
Green, NG .
BIOPHYSICAL JOURNAL, 1999, 77 (01) :516-525
[12]   Applications of dielectrophoresis in biotechnology [J].
Pethig, R ;
Markx, GH .
TRENDS IN BIOTECHNOLOGY, 1997, 15 (10) :426-432
[13]  
PETHIG R, 1991, AUTOMATION IN BIOTECHNOLOGY, P159
[14]  
Pethig R., 1979, DIELECTRIC ELECT PRO
[15]  
Pohl, 1978, DIELECTROPHORESIS
[16]   ELECTROCHEMICAL OXIDATION OF L-ASCORBIC-ACID AT THE GRAPHITE ELECTRODE AND ITS MONITORING BY A THICK-FILM GRAPHITE SENSOR ASSEMBLY [J].
XING, XK ;
TAN, TC ;
SHAO, M ;
LIU, CC .
ELECTROANALYSIS, 1992, 4 (02) :191-197
[17]  
Xu CX, 1999, ELECTROPHORESIS, V20, P1829, DOI 10.1002/(SICI)1522-2683(19990701)20:9<1829::AID-ELPS1829>3.0.CO
[18]  
2-B