Paraneoplastic Gastro-Intestinal Anti-Hu Syndrome in Neuroblastoma

被引：19

作者：

Drukker, C. A. M. ^{[1
]}

Heij, H. A. ^{[2
]}

Wijnaendts, L. C. D. ^{[3
]}

Verbeke, J. I. M. L. ^{[4
]}

Kaspers, G. J. L. ^{[1
]}

机构：

[1] Vrije Univ Amsterdam Med Ctr, Dept Pediat Oncol Hematol, NL-1081 HV Amsterdam, Netherlands

[2] Vrije Univ Amsterdam Med Ctr, Pediat Surg Ctr Amsterdam, NL-1081 HV Amsterdam, Netherlands

[3] Vrije Univ Amsterdam Med Ctr, Dept Pathol, NL-1081 HV Amsterdam, Netherlands

[4] Vrije Univ Amsterdam Med Ctr, Dept Radiol, NL-1081 HV Amsterdam, Netherlands

来源：

PEDIATRIC BLOOD & CANCER | 2009年 / 52卷 / 03期

关键词：

anti-Hu antibodies; anti-Hu syndrome; gastro-intestinal disturbances; neuroblastoma; paraneoplastic syndrome; INTESTINAL PSEUDOOBSTRUCTION; ANTIBODIES; NEURONOPATHY;

D O I：

10.1002/pbc.21807

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The anti-Hu syndrome is a well-known paraneoplastic syndrome and may be rarely seen in patients with neuroblastoma. However, it is relatively unknown that anti-Hu antibodies call cause gastrointestinal signs and symptoms. We report on a child with neuroblastoma who presented with gastro-intestinal disturbances as a result of the anti-HU syndrome and summaries two similar case reports reported in literature. Neuroblastoma patients with gastrointestinal disturbances, ranging from constipation to a paralytic ileus, might suffer from the gastro-intestinal anti-HU syndrome. The causative antibodies call be determined to diagnose or exclude this syndrome, and successful treatment is possible. Pediatr Blood Cancer 2009;52:396-398. (C) 2008 Wiley-Liss, Inc.

引用

页码：396 / 398

页数：3

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