Novel concise synthesis of 2-substituted 3,4-dihydro-2H-1,4-benzoxazines by ring opening of glycidols under solid-liquid phase transfer catalysis conditions

被引：28

作者：

Albanese, D

Landini, D

Penso, M

机构：

[1] Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy

[2] Univ Milan, Ctr CNR, I-20133 Milan, Italy

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 20期

关键词：

D O I：

10.1039/a906260b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The ring opening of glycidols with N-(2-fluorophenyl)toluene-p-sulfonamide under SL-PTC conditions, followed by ring closure with (BuOK)-O-t, provides a novel high yielding synthesis of 2-substituted 3,4-dihydro-2H-1,4-benzoxazines.

引用

页码：2095 / 2096

页数：2

共 16 条

[11] Johnson R.A., 1993, CATALYTIC ASYMMETRIC
[12] Kuroita T, 1996, CHEM PHARM BULL, V44, P756
[13] NOVEL 1,4-BENZOXAZINE DERIVATIVES OF PHARMACOLOGICAL INTEREST - ELECTROCHEMICAL AND CHEMICAL SYNTHESES
LARGERON, M
DUPUY, H
FLEURY, MB
[J]. TETRAHEDRON, 1995, 51 (17) : 4953 - 4968
[14] Lhoste P, 1997, B SOC CHIM FR, V134, P343
[15] Matsumoto Y, 1996, CHEM PHARM BULL, V44, P103
[16] Asymmetric cyclization of 3,4-dihydro-2-vinyl-2H-1,4-benzoxazine catalyzed by palladium-BHMP catalyst
Yamazaki, A
Achiwa, I
Achiwa, K
[J]. TETRAHEDRON-ASYMMETRY, 1996, 7 (02) : 403 - 406

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