A hydrocarbon anchored peptide that forms a chloride- selective channel in liposomes

被引：38

作者：

Schlesinger, PH

Ferdani, R

Pajewski, R

Pajewska, J

Gokel, GW

机构：

[1] Washington Univ, Sch Med, Dept Cell Biol, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Div Bioorgan Chem, Bioorgan Chem Program, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Dept Mol Biol & Pharmacol, St Louis, MO 63110 USA

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 08期

关键词：

D O I：

10.1039/b200126h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The heptapeptide sequence Gly-Gly-Gly-Pro-Gly-Gly-Gly, when anchored to diglycolic acid derived (C18H37)(2)NCOCH2OCH2COOH, forms chloride-selective ion channels in phospholipid liposomes but the related heptapeptide GlyGly-Gly-Leu-Gly-Gly-Gly, and tripeptide Gly-Gly-Gly do not.

引用

收藏

页码：840 / 841

页数：2

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