Reappraisal of the regulation of lactococcal L-lactate dehydrogenase

被引:19
作者
van Niel, EWJ [1 ]
Palmfeldt, J [1 ]
Martin, R [1 ]
Paese, M [1 ]
Hahn-Hägerdal, B [1 ]
机构
[1] Lund Univ, Dept Appl Microbiol, SE-22100 Lund, Sweden
关键词
D O I
10.1128/AEM.70.3.1843-1846.2004
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Lactococcal lactate dehydrogenases (LDHs) are coregulated at the substrate level by at least two mechanisms: the fructose- 1,6-biphosphate/phosphate ratio and the NADH/NAD ratio. Among the Lactococcus lactis species, there are strains that are predominantly regulated by the first mechanism (e.g., strain 65.1) or by the second mechanism (e.g., strain NCDO 2118). A more complete model of the kinetics of the regulation of lactococcal LDH is discussed.
引用
收藏
页码:1843 / 1846
页数:4
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