Achieving natural product synthesis and diversity via catalytic networking ex vivo

被引：33

作者：

Roessner, CA

Scott, AI

机构：

来源：

CHEMISTRY & BIOLOGY | 1996年 / 3卷 / 05期

关键词：

D O I：

10.1016/S1074-5521(96)90114-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent studies on ex vivo synthesis of natural products reveal that even complex multistep pathways can be successfully reconstructed. Genetic engineering of such reconstituted pathways has already been used to generate 'unnatural' natural products related to the original compound. In the future, it may be possible to use these approaches to make natural products that are currently inaccessible to conventional synthesis.

引用

页码：325 / 330

页数：6

共 31 条

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