The chick embryo chorioallantoic membrane as a model to study tumor metastasis

被引:82
作者
Cimpean, Anca Maria [2 ]
Ribatti, Domenico [1 ]
Raica, Marius [2 ]
机构
[1] Univ Bari, Dept Human Anat & Histol, Sch Med, Policlin, I-70124 Bari, Italy
[2] Victor Babes Univ Med & Pharm Timisoara, Dept Histol, Timisoara, Romania
关键词
Angiogenesis; Anti-angiogenesis; Chorioallantoic membrane; Metastasis; Tumor progression;
D O I
10.1007/s10456-008-9117-1
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Tumor metastasis represents a major problem in the treatment of patients with different cancers. Specific phenotype and behavior of metastatic cells derive from specific molecular mechanisms involved in consecutive steps of the metastatic process. Several in vitro and in vivo experimental models have been utilized, but they cannot completely reproduce and characterize each step of the metastatic process. This review article is focused on the chick embryo chorioallantoic membrane as an in vivo model to study the metastatic process.
引用
收藏
页码:311 / 319
页数:9
相关论文
共 65 条
[1]  
[Anonymous], 1960, AVIAN EMBRYO STRUCTU
[2]   Angiogenesis assays: A critical overview [J].
Auerbach, R ;
Lewis, R ;
Shinners, B ;
Kubai, L ;
Akhtar, N .
CLINICAL CHEMISTRY, 2003, 49 (01) :32-40
[3]   SIMPLE PROCEDURE FOR LONG-TERM CULTIVATION OF CHICKEN EMBRYOS [J].
AUERBACH, R ;
KUBAI, L ;
KNIGHTON, D ;
FOLKMAN, J .
DEVELOPMENTAL BIOLOGY, 1974, 41 (02) :391-394
[4]   DIFFERENTIATION OF VASCULAR ENDOTHELIUM IN CHICK CHORIOALLANTOIS - STRUCTURAL AND AUTORADIOGRAPHIC STUDY [J].
AUSPRUNK, DH ;
KNIGHTON, DR ;
FOLKMAN, J .
DEVELOPMENTAL BIOLOGY, 1974, 38 (02) :237-248
[5]   Development of a green fluorescent protein metastatic-cancer chick-embryo drug-screen model [J].
Bobek, V ;
Plachy, J ;
Pinterova, D ;
Kolostova, K ;
Boubelik, M ;
Jiang, P ;
Yang, M ;
Hoffman, RM .
CLINICAL & EXPERIMENTAL METASTASIS, 2004, 21 (04) :347-352
[6]   SUBTRACTIVE IMMUNIZATION YIELDS MONOCLONAL-ANTIBODIES THAT SPECIFICALLY INHIBIT METASTASIS [J].
BROOKS, PC ;
LIN, JM ;
FRENCH, DL ;
QUIGLEY, JP .
JOURNAL OF CELL BIOLOGY, 1993, 122 (06) :1351-1359
[7]   A virus disease of the canary of the fowl pox group [J].
Burnet, FM .
JOURNAL OF PATHOLOGY AND BACTERIOLOGY, 1933, 37 (01) :107-122
[8]  
CHAMBERS AF, 1982, CANCER RES, V42, P4018
[9]   EARLY STEPS IN HEMATOGENOUS METASTASIS OF B16F1 MELANOMA-CELLS IN CHICK-EMBRYOS STUDIED BY HIGH-RESOLUTION INTRAVITAL VIDEOMICROSCOPY [J].
CHAMBERS, AF ;
SCHMIDT, EE ;
MACDONALD, IC ;
MORRIS, VL ;
GROOM, AC .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1992, 84 (10) :797-803
[10]   Technique of operating on chick embryos [J].
Clark, ER .
SCIENCE, 1920, 51 :371-373