The chick embryo chorioallantoic membrane as a model to study tumor metastasis

被引：82

作者：

Cimpean, Anca Maria ^{[2
]}

Ribatti, Domenico ^{[1
]}

Raica, Marius ^{[2
]}

机构：

[1] Univ Bari, Dept Human Anat & Histol, Sch Med, Policlin, I-70124 Bari, Italy

[2] Victor Babes Univ Med & Pharm Timisoara, Dept Histol, Timisoara, Romania

来源：

ANGIOGENESIS | 2008年 / 11卷 / 04期

关键词：

Angiogenesis; Anti-angiogenesis; Chorioallantoic membrane; Metastasis; Tumor progression;

D O I：

10.1007/s10456-008-9117-1

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Tumor metastasis represents a major problem in the treatment of patients with different cancers. Specific phenotype and behavior of metastatic cells derive from specific molecular mechanisms involved in consecutive steps of the metastatic process. Several in vitro and in vivo experimental models have been utilized, but they cannot completely reproduce and characterize each step of the metastatic process. This review article is focused on the chick embryo chorioallantoic membrane as an in vivo model to study the metastatic process.

引用

页码：311 / 319

页数：9

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