Synthesis, antimicrobial and molluscicidal activities of new benzimidazole derivatives

被引：43

作者：

Nofal, ZM ^{[1
]}

Fahmy, HH ^{[1
]}

Mohamed, HS ^{[1
]}

机构：

[1] Natl Res Ctr, Dept Theoret Chem, Cairo, Egypt

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2002年 / 25卷 / 01期

关键词：

Schiffs bases; thiosemicarbazides 1,3,4-triazole; 1,3,4-oxadiazole; pyrimidinobenzimidazoles; triazinobenzimldazoles;

D O I：

10.1007/BF02975257

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of benzimidazole Schiff's bases, thiosemicarbazides were synthesized, azole ring systems as 1,3,4-triazole, 1,3,4-oxadiazole were prepared. 1-Methylbenzimidazole incorporated to substituted dithio-carbamate, thiophenol, diethylamine via acetamido group were synthesized. A series of pyrimidinobenzimidazoles, triazinobenz-imidazoles, and 2-(acetonylamino)-1-methyl-benzimidazole were prepared. The antimicrobial and molluscicidal activities of some newly prepared compounds were carried out.

引用

页码：28 / 38

页数：11

共 28 条

[1]

Abbas S.E., 1991, EGYPT, V32, P503

[2]

ABDOU OA, 1987, ARCH PHARM WEINHEIM, V320, P642

[3] BENZO[B]THIOPHENES .1. SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF BENZO[B]THIENYL-1,3,4-OXADIAZOLE, BENZO[B]THIENYL-1,2,4-TRIAZOLINE, AND BENZO[B]THIENYL-THIAZOLINE DERIVATIVES [J].