Microwave-promoted aminocarbonylation of aryl triflates using Mo(CO)6 as a solid CO source

被引：55

作者：

Odell, Luke R. ^{[1
]}

Savmarker, Jonas ^{[1
]}

Larhed, Mats ^{[1
]}

机构：

[1] Uppsala Univ, Dept Med Chem, Uppsala Biomed Ctr, SE-75123 Uppsala, Sweden

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 42期

基金：

瑞典研究理事会;

关键词：

carbonylation; microwave; palladium; aryl triflate; DMAP;

D O I：

10.1016/j.tetlet.2008.08.014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed carbonylations of aryl triflates with a range of nucleophiles using Mo(CO)(6) as a solid CO source were explored. The reactions proceeded smoothly providing moderate to good yields of the corresponding aryl amides, esters, or acylsulfonamides after only 20 min of microwave irradiation. The acyl transfer reagent 4-dimethylaminopyridine was found to promote some of the more difficult transformations. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：6115 / 6118

页数：4

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