Optically active cyclic hexapeptides with covalently attached pyrene probes: Selective alkaline earth metal ion recognition using excimer emission

被引：38

作者：

Strauss, J ^{[1
]}

Daub, J ^{[1
]}

机构：

[1] Univ Regensburg, Inst Organ Chem, D-93053 Regensburg, Germany

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 05期

关键词：

D O I：

10.1021/ol0170354

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The synthesis of two optically active pyrene-modified cyclic hexapetides and their selectivity toward the complexation of alkaline earth metal ions are reported. Complexation was studied by optical and chiroptical methods. The cyclic peptides are forming 2:1 sandwich complexes with the metal ions.

引用

页码：683 / 686

页数：4

共 41 条

[31] THE INTERACTION BETWEEN PROTEIN-KINASE-C AND LIPID COFACTORS STUDIED BY SIMULTANEOUS OBSERVATION OF LIPID AND PROTEIN FLUORESCENCE
PAP, EHW
VANDENBERG, PAW
BORST, JW
VISSER, AJWG
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (03) : 1254 - 1260
[32] LIPID TUBULES - A PARADIGM FOR MOLECULARLY ENGINEERED STRUCTURES
SCHNUR, JM
[J]. SCIENCE, 1993, 262 (5140) : 1669 - 1676
[33] PHOTOINDUCED ELECTRON-TRANSFER ON A SINGLE ALPHA-HELICAL POLYPEPTIDE-CHAIN
SISIDO, M
TANAKA, R
INAI, Y
IMANISHI, Y
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (17) : 6790 - 6796
[34] A sensitive and rapid fluorescence-based assay for determination of tetanus toxin peptidase activity
Soleilhac, JM
Cornille, F
Martin, L
Lenoir, C
FournieZaluski, MC
Roques, BP
[J]. ANALYTICAL BIOCHEMISTRY, 1996, 241 (01) : 120 - 127
[35] New fluorimetric alkali and alkaline earth metal cation sensors based on noncyclic crown ethers by means of intramolecular excimer formation of pyrene
Suzuki, Y
Morozumi, T
Nakamura, H
Shimomura, M
Hayashita, T
Bartsh, RA
[J]. JOURNAL OF PHYSICAL CHEMISTRY B, 1998, 102 (40): : 7910 - 7917
[36] DESTABILIZATION OF THE HEME REGION IN MUTANT CYTOCHROME-C BY REPLACEMENT OF PHE-82 WITH 3-(PYREN-1-YL)-L-ALANINE
UEDA, T
KIMURA, S
IMANISHI, Y
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1995, (02): : 359 - 363
[37] Bispyrene based chiroptical molecular redox switch
Westermeier, C
Gallmeier, HC
Komma, M
Daub, J
[J]. CHEMICAL COMMUNICATIONS, 1999, (23) : 2427 - 2428
[38] PHOTOPHYSICS OF PREASSOCIATED PYRENES IN AQUEOUS POLYMER-SOLUTIONS AND IN OTHER ORGANIZED MEDIA
WINNIK, FM
[J]. CHEMICAL REVIEWS, 1993, 93 (02) : 587 - 614
[39] CONFORMATIONAL STUDIES OF CYCLO-(-PRO-GLY-)(3) AND ITS COMPLEXES WITH CATIONS BY VIBRATIONAL CIRCULAR-DICHROISM
XIE, P
DIEM, M
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (01) : 429 - 437
[40] Selective potassium ion recognition by benzo-15-crown-5 fluoroionophore/y-cyclodextrin complex sensors in water
Yamauchi, A
Hayashita, T
Kato, A
Nishizawa, S
Watanabe, M
Teramae, N
[J]. ANALYTICAL CHEMISTRY, 2000, 72 (23) : 5841 - 5846

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