Fast-track surgery improves postoperative recovery in patients undergoing partial hepatectomy for primary liver cancer: A prospective randomized controlled trial

被引:116
作者
Ni, C. Y. [1 ]
Yang, Y. [1 ,2 ]
Chang, Y. Q. [1 ]
Cai, H. [1 ]
Xu, B. [1 ]
Yang, F. [1 ]
Lau, W. Y. [3 ]
Wang, Z. H. [1 ]
Zhou, W. P. [1 ,4 ]
机构
[1] Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Shanghai 200438, Peoples R China
[2] Second Mil Med Univ, Dept Hlth Stat, Shanghai 200438, Peoples R China
[3] Chinese Univ Hong Kong, Fac Med, Shatin, Hong Kong, Peoples R China
[4] Natl Innovat Alliance Hepatitis & Liver Canc, Shanghai, Peoples R China
来源
EJSO | 2013年 / 39卷 / 06期
关键词
Perioperative care; Fast track surgery; Liver neoplasm; Rehabilitation; Hepatectomy; PERIOPERATIVE CARE; SURGICAL COMPLICATIONS; COLORECTAL SURGERY; GASTRIC-CANCER; CLINICAL-TRIAL; PROGRAM; MANAGEMENT; RESECTION; OUTCOMES; CLASSIFICATION;
D O I
10.1016/j.ejso.2013.03.013
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background and aim: Fast-track surgery (FTS), combining several techniques with evidence-based adjustments, has shown its effectiveness to accelerate recovery, reduce morbidity and shorten hospital stay in many operations. This randomized controlled study was carried out aiming to compare the short-term outcomes of partial hepatectomy for liver cancer managed with FTS or with conventional surgery (CS). Methods: To compare the short-term effects between FTS and CS, a randomized controlled trial was carried out for liver cancer patients undergoing partial hepatectomy from September 2010 to June 2012. Results: Patients with liver cancers before receiving partial hepatectomy were randomized into the FTS group (n = 80) and the CS group (n = 80). Compared with the CS group, the FTS group had significantly less complications (P < 0.05), shorter durations of nausea/vomiting, paralytic ileus and hospital stay, higher general comfort questionnaire measures (GCQ) by Kolcaba Line (all P < 0.05), and lower serum levels of C-reactive Protein on postoperative days 1, 3, and 5. Conclusions: FTS was safe and efficacious. It lessened postoperative stress reactions and accelerated recovery for patients undergoing partial hepatectomy for liver cancer. (c) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:542 / 547
页数:6
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