Fast-track surgery improves postoperative recovery in patients undergoing partial hepatectomy for primary liver cancer: A prospective randomized controlled trial

被引：116

作者：

Ni, C. Y. ^{[1
]}

Yang, Y. ^{[1
,2
]}

Chang, Y. Q. ^{[1
]}

Cai, H. ^{[1
]}

Xu, B. ^{[1
]}

Yang, F. ^{[1
]}

Lau, W. Y. ^{[3
]}

Wang, Z. H. ^{[1
]}

Zhou, W. P. ^{[1
,4
]}

机构：

[1] Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Shanghai 200438, Peoples R China

[2] Second Mil Med Univ, Dept Hlth Stat, Shanghai 200438, Peoples R China

[3] Chinese Univ Hong Kong, Fac Med, Shatin, Hong Kong, Peoples R China

[4] Natl Innovat Alliance Hepatitis & Liver Canc, Shanghai, Peoples R China

来源：

EJSO | 2013年 / 39卷 / 06期

关键词：

Perioperative care; Fast track surgery; Liver neoplasm; Rehabilitation; Hepatectomy; PERIOPERATIVE CARE; SURGICAL COMPLICATIONS; COLORECTAL SURGERY; GASTRIC-CANCER; CLINICAL-TRIAL; PROGRAM; MANAGEMENT; RESECTION; OUTCOMES; CLASSIFICATION;

D O I：

10.1016/j.ejso.2013.03.013

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background and aim: Fast-track surgery (FTS), combining several techniques with evidence-based adjustments, has shown its effectiveness to accelerate recovery, reduce morbidity and shorten hospital stay in many operations. This randomized controlled study was carried out aiming to compare the short-term outcomes of partial hepatectomy for liver cancer managed with FTS or with conventional surgery (CS). Methods: To compare the short-term effects between FTS and CS, a randomized controlled trial was carried out for liver cancer patients undergoing partial hepatectomy from September 2010 to June 2012. Results: Patients with liver cancers before receiving partial hepatectomy were randomized into the FTS group (n = 80) and the CS group (n = 80). Compared with the CS group, the FTS group had significantly less complications (P < 0.05), shorter durations of nausea/vomiting, paralytic ileus and hospital stay, higher general comfort questionnaire measures (GCQ) by Kolcaba Line (all P < 0.05), and lower serum levels of C-reactive Protein on postoperative days 1, 3, and 5. Conclusions: FTS was safe and efficacious. It lessened postoperative stress reactions and accelerated recovery for patients undergoing partial hepatectomy for liver cancer. (c) 2013 Elsevier Ltd. All rights reserved.

引用

页码：542 / 547

页数：6

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