High rate of intestinal colonization with extended-spectrum-β-lactamase-producing organisms in household contacts of infected community patients

被引:142
作者
Valverde, Aranzazu [1 ,2 ]
Grill, Fabio [3 ]
Coque, Teresa M. [1 ,2 ]
Pintado, Vicente [3 ]
Baquero, Fernando [1 ,2 ]
Canton, Rafael [1 ,2 ]
Cobo, Javier [3 ]
机构
[1] Hosp Univ Ramon & Cajal, Microbiol Serv, Madrid 28034, Spain
[2] Hosp Univ Ramon & Cajal, CIBERESP, Madrid 28034, Spain
[3] Hosp Univ Ramon & Cajal, Serv Enfermedades Infecciosas, Madrid 28034, Spain
关键词
D O I
10.1128/JCM.01008-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Fecal carriage of extended-spectrum-beta-lactamase (ESBL)-producing organisms was detected in 70% of index cases of patients (n = 40) with community-acquired infections due to ESBL producers and reached 16.7% in household contacts (n = 54). A total of 66% of ESBL-producing organisms from index cases were indistinguishable from isolates from household contacts by pulsed-field gel electrophoresis. Patients with community infections and members of their households represent a reservoir for ESBL producers, increasing dispersal of resistance in healthy people.
引用
收藏
页码:2796 / 2799
页数:4
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