Lymphoid organ development: from ontogeny to neogenesis

被引：550

作者：

Drayton, DL

Liao, S

Mounzer, RH

Ruddle, NH ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Immunobiol Sect, New Haven, CT 06520 USA

[2] Yale Univ, Sch Med, Dept Epidemiol & Publ Hlth, New Haven, CT 06520 USA

来源：

NATURE IMMUNOLOGY | 2006年 / 7卷 / 04期

关键词：

D O I：

10.1038/ni1330

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The development of lymphoid organs can be viewed as a continuum. At one end are the `canonical' secondary lymphoid organs, including lymph nodes and spleen; at the other end are `ectopic' or tertiary lymphoid organs, which are cellular accumulations arising during chronic inflammation by the process of lymphoid neogenesis. Secondary lymphoid organs are genetically `preprogrammed' and `prepatterned' during ontogeny, whereas tertiary lymphoid organs arise under environmental influences and are not restricted to specific developmental `windows' or anatomic locations. Between these two boundaries are other types of lymphoid tissues that are less developmentally but more environmentally regulated, such as Peyer's patches, nasal-associated lymphoid tissue, bronchial-associated lymphoid tissue and inducible bronchial-associated lymphoid tissue. Their regulation, functions and potential effects are discussed here.

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收藏

页码：344 / 353

页数：10

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共 162 条

[81] The TNF and TNF receptor superfamilies: Integrating mammalian biology [J].

Locksley, RM ;

Killeen, N ;

Lenardo, MJ .

CELL, 2001, 104 (04) :487-501

[82] Isolated lymphoid follicles can function as sites for induction of mucosal immune responses [J].

Lorenz, RG ;

Newberry, RD .

ORAL TOLERANCE: NEW INSIGHTS AND PROSPECTS FOR CLINICAL APPLICATION, 2004, 1029 :44-57

[83] Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse [J].

Luther, SA ;

Tang, HL ;

Hyman, PL ;

Farr, AG ;

Cyster, JG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (23) :12694-12699

[84] Overlapping roles of CXCL13, interleukin 7 receptor α, and CCR7 ligands in lymph node development [J].

Luther, SA ;

Ansel, KM ;

Cyster, JG .

JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 197 (09) :1191-1198

[85] Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis [J].

Luther, SA ;

Bidgol, A ;

Hargreaves, DC ;

Schmidt, A ;

Xu, Y ;

Paniyadi, J ;

Matloubian, M ;

Cyster, JG .

JOURNAL OF IMMUNOLOGY, 2002, 169 (01) :424-433

[86] Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis [J].

Magliozzi, R ;

Columba-Cabezas, S ;

Serafini, B ;

Aloisi, F .

JOURNAL OF NEUROIMMUNOLOGY, 2004, 148 (1-2) :11-23

[87] The alpha(1,3)Fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis [J].

Maly, P ;

Thall, AD ;

Petryniak, B ;

Rogers, GE ;

Smith, PL ;

Marks, RM ;

Kelly, RJ ;

Gersten, KM ;

Cheng, GY ;

Saunders, TL ;

Camper, SA ;

Camphausen, RT ;

Sullivan, FX ;

Isogai, Y ;

Hindsgaul, O ;

vonAndrian, UH ;

Lowe, JB .

CELL, 1996, 86 (04) :643-653

[88] A novel model for lymphocytic infiltration of the thyroid gland generated by transgenic expression of the CC chemokine CCL21 [J].

Martin, AP ;

Coronel, EC ;

Sano, G ;

Chen, SC ;

Vassileva, G ;

Canasto-Chibuque, C ;

Sedgwick, JD ;

Frenette, PS ;

Lipp, M ;

Furtado, GC ;

Lira, SA .

JOURNAL OF IMMUNOLOGY, 2004, 173 (08) :4791-4798

[89] Inflammation-induced lymphangiogenesis in the cornea arises from CD11 b-positive macrophages [J].

Maruyama, K ;

Li, M ;

Cursiefen, C ;

Jackson, DG ;

Keino, H ;

Tomita, M ;

Van Rooijen, N ;

Takenaka, H ;

D'Amore, PA ;

Stein-Streilein, J ;

Losordo, DW ;

Streilein, JW .

JOURNAL OF CLINICAL INVESTIGATION, 2005, 115 (09) :2363-2372

[90] BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphoma [J].

Mazzucchelli, L ;

Blaser, A ;

Kappeler, A ;

Schärli, P ;

Laissue, JA ;

Baggiolini, M ;

Uguccioni, M .

JOURNAL OF CLINICAL INVESTIGATION, 1999, 104 (10) :R49-R54

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