Kawaguchipeptin B, an antibacterial cyclic undecapeptide from the cyanobacterium Microcystis aeruginosa

被引：86

作者：

Ishida, K ^{[1
]}

Matsuda, H ^{[1
]}

Murakami, M ^{[1
]}

Yamaguchi, K ^{[1
]}

机构：

[1] UNIV TOKYO,GRAD SCH AGR LIFE SCI,MARINE BIOCHEM LAB,BUNKYO KU,TOKYO 113,JAPAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 07期

关键词：

D O I：

10.1021/np970146k

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Kawaguchipeptin B, an antibacterial cyclic undecapeptide, was isolated from the cultured cyanabacterium Microcystis aeruginosa (NIES-88). Its structure was elucidated as 1 on the basis of 2D NMR data and chemical degradation. Kawaguchipegtin B (1) inhibited the growth of the Gram-positive bacterium Staphylococcus aureus at a concentration of 1 mu g/mL (MIC).

引用

页码：724 / 726

页数：3

共 20 条

[11] DETERMINATION OF D-AMINO ACIDS .2. USE OF A BIFUNCTIONAL REAGENT, 1,5-DIFLUORO-2,4-DINITROBENZENE [J].

MARFEY, P .

CARLSBERG RESEARCH COMMUNICATIONS, 1984, 49 (06) :591-596

[12] CYANOPEPTOLINS, NEW DEPSIPEPTIDES FROM THE CYANOBACTERIUM MICROCYSTIS SP PCC 7806 [J].

MARTIN, C ;

OBERER, L ;

INO, T ;

KONIG, WA ;

BUSCH, M ;

WECKESSER, J .

JOURNAL OF ANTIBIOTICS, 1993, 46 (10) :1550-1556

[13]

MURAKAMI M, 1995, TETRAHEDRON LETT, V36, P3535

[14] RECOVERY OF TRYPTOPHAN IN PEPTIDES AND PROTEINS BY HIGH-TEMPERATURE AND SHORT-TERM ACID-HYDROLYSIS IN THE PRESENCE OF PHENOL [J].

MURAMOTO, K ;

KAMIYA, H .

ANALYTICAL BIOCHEMISTRY, 1990, 189 (02) :223-230

[15] MICROGININ, AN ANGIOTENSIN-CONVERTING ENZYME-INHIBITOR FROM THE BLUE-GREEN-ALGA MICROCYSTIS-AERUGINOSA [J].

OKINO, T ;

MATSUDA, H ;

MURAKAMI, M ;

YAMAGUCHI, K .

TETRAHEDRON LETTERS, 1993, 34 (03) :501-504

[16] NEW MICROVIRIDINS, ELASTASE INHIBITORS FROM THE BLUE-GREEN-ALGA MICROCYSTIS-AERUGINOSA [J].

OKINO, T ;

MATSUDA, H ;

MURAKAMI, M ;

YAMAGUCHI, K .

TETRAHEDRON, 1995, 51 (39) :10679-10686

[17] MICROPEPTIN-A AND MICROPEPTIN-B, PLASMIN AND TRYPSIN-INHIBITORS FROM THE BLUE-GREEN-ALGA MICROCYSTIS-AERUGINOSA [J].

OKINO, T ;

MURAKAMI, M ;

HARAGUCHI, R ;

MUNEKATA, H ;

MATSUDA, H ;

YAMAGUCHI, K .

TETRAHEDRON LETTERS, 1993, 34 (50) :8131-8134

[18] MICROCYSTILIDE-A - A NOVEL CELL-DIFFERENTIATION-PROMOTING DEPSIPEPTIDE FROM MICROCYSTIS-AERUGINOSA NO-15-1840 [J].

TSUKAMOTO, S ;

PAINULY, P ;

YOUNG, KA ;

YANG, XM ;

SHIMIZU, Y ;

CORNELL, L .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (23) :11046-11047

[19]

WATANABE MM, 1991, NIES COLLECTION LIST, P32

[20]

WATANABE MM, 1984, JPN J FREEZ DRY, V30, P23

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