Phagocytes: mechanisms of inflammation and tissue destruction

被引：32

作者：

Liu, HT

Pope, RM

机构：

[1] Northwestern Univ, Feinberg Sch Med, Dept Med, Div Rheumatol, Chicago, IL 60611 USA

[2] Vet Affairs Med Ctr, Chicago, IL USA

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2004年 / 30卷 / 01期

关键词：

D O I：

10.1016/S0889-857X(03)00107-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Macrophages and neutrophils are the professional phagocytes of the innate immune system. Once in the inflammatory joint or the vasculitic lesion, macrophages and neutrophils contribute to the pathology observed. This article examines the mechanisms by which phagocytes contribute to the pathogenesis of these diseases.

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页码：19 / +

页数：22

相关论文

共 78 条

[21] Alternative activation of macrophages [J].

Gordon, S .

NATURE REVIEWS IMMUNOLOGY, 2003, 3 (01) :23-35

[22] Novel pathways that regulate tumor necrosis factor-α production in rheumatoid arthritis [J].

Gracie, JA ;

Leung, BP ;

McInnes, IB .

CURRENT OPINION IN RHEUMATOLOGY, 2002, 14 (03) :270-275

[23] Alternatively activated macrophages differentially express fibronectin and its splice variants and the extracellular matrix protein βIG-H3 [J].

Gratchev, A ;

Guillot, P ;

Hakiy, N ;

Politz, O ;

Orfanos, CE ;

Schledzewski, K ;

Goerdt, S .

SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 2001, 53 (04) :386-392

[24] Antineutrophil cytoplasmic antibodies induce reactive oxygen-dependent dysregulation of primed neutrophil apoptosis and clearance by macrophages [J].

Harper, L ;

Ren, Y ;

Savill, J ;

Adu, D ;

Savage, COS .

AMERICAN JOURNAL OF PATHOLOGY, 2000, 157 (01) :211-220

[25]

Harper L, 2001, ARTHRITIS RHEUM-US, V44, P921, DOI 10.1002/1529-0131(200104)44:4<921::AID-ANR149>3.3.CO

[26]

2-W

[27] Glycosulfopeptides modeled on P-selectin glycoprotein ligand-1 inhibit P-selectin-dependent leukocyte rolling in vivo [J].

Hicks, AER ;

Leppänen, A ;

Cummings, RD ;

McEver, RP ;

Hellewell, PG ;

Norman, KE .

FASEB JOURNAL, 2002, 16 (09) :1461-+

[28] IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation [J].

Hurst, SM ;

Wilkinson, TS ;

McLoughlin, RM ;

Jones, S ;

Horiuchi, S ;

Yamamoto, N ;

Rose-John, S ;

Fuller, GM ;

Topley, N ;

Jones, SA .

IMMUNITY, 2001, 14 (06) :705-714

[29] Arthritis critically dependent on innate immune system players [J].

Ji, H ;

Ohmura, K ;

Mahmood, U ;

Lee, DM ;

Hofhuis, FMA ;

Boackle, SA ;

Takahashi, K ;

Holers, VM ;

Walport, M ;

Gerard, C ;

Ezekowitz, A ;

Carroll, MC ;

Brenner, M ;

Weissleder, R ;

Verbeek, JS ;

Duchatelle, V ;

Degott, C ;

Benoist, C ;

Mathis, D .

IMMUNITY, 2002, 16 (02) :157-168

[30]

Johnson-Léger C, 2000, J CELL SCI, V113, P921

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