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Clickphine: A novel and highly versatile P,N ligand class via click chemistry

被引：142
作者：
Detz, Remko J.
Arevalo Heras, Silvia
de Gelder, R.
van Leeuwen, Piet W. N. M.
Hiemstra, Henk
Reek, Joost N. H.
van Maarseveen, Jan H.
机构：
[1] Radboud Univ Nijmegen, Inst Mol & Mat, NL-6525 ED Nijmegen, Netherlands
[2] Univ Amsterdam, Fac Sci, Vant Hoff Inst Mol Sci, NL-1018 WS Amsterdam, Netherlands
来源：
ORGANIC LETTERS | 2006年 / 8卷 / 15期
关键词：
D O I：
10.1021/ol061015q
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel P,N-type ligand family (ClickPhine) is disclosed that is easily accessible using the Cu(I)-catalyzed azide-alkyne "click" cycloaddition. A diverse set of ligands was made in just three steps from readily available starting materials to give several homogeneous and a heterogeneous catalyst. Preliminary experiments show the efficacy of these ligands in the Pd-catalyzed allylic alkylation reaction.
引用
收藏
页码：3227 / 3230
页数：4
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