Molecular and physical characterization of Burkholderia mallei O antigens

被引:55
作者
Burtnick, MN [1 ]
Brett, PJ [1 ]
Woods, DE [1 ]
机构
[1] Univ Calgary, Hlth Sci Ctr, Dept Microbiol & Infect Dis, Calgary, AB T2N 4N1, Canada
关键词
D O I
10.1128/JB.184.3.849-852.2002
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Burkholderia mallei lipopolysaccharide (LPS) has been previously shown to cross-react with polyclonal antibodies raised against B. pseudomallei LPS; however, we observed that B. mallei LPS does not react with a monoclonal antibody (Pp-PS-W) specific for B. pseudomallei 0 polysaccharide, (O-PS). In this study, we identified the O-PS biosynthetic gene cluster from B. mallei ATCC 23344 and subsequently characterized the molecular structure of the O-PS produced by this organism.
引用
收藏
页码:849 / 852
页数:4
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