Synthesis of Single-Chain Sugar Arrays

被引：53

作者：

Baradel, Nathalie ^{[1
]}

Fort, Sebastien ^{[2
]}

Halila, Sami ^{[2
]}

Badi, Nezha ^{[1
]}

Lutz, Jean-Francois ^{[1
]}

机构：

[1] Inst Charles Sadron, CNRS UPR22, F-67034 Strasbourg 2, France

[2] CERMAV CNRS, Ctr Rech Macromol Vegetales, F-38041 Grenoble 9, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 08期

基金：

欧洲研究理事会;

关键词：

biohybrid copolymers; glycopolymers; radical copolymerization; sequence-controlled polymers; single-chain arrays; CLICK CHEMISTRY; POLYMER; SEQUENCE; CYCLOADDITION; NANOPARTICLES; COPPER; COPOLYMERIZATION; GLYCOPOLYMERS; LIGATION; COVALENT;

D O I：

10.1002/anie.201209052

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Polymers that toe the line: Well-defined linear polystyrene chains containing precisely positioned hexose moieties (mannose, galactose, and N-acetylglucosamine) were synthesized by a sequence-controlled polymerization approach followed by a series of site-selective modification steps. Such multifunctional single-chain hexose arrays associate specifically with complementary lectins (see picture). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：2335 / 2339

页数：5

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