Mathematical models and lymphatic filariasis control: endpoints and optimal interventions

被引：68

作者：

Michael, Edwin

Malecela-Lazaro, Mwele N.

Kabali, Conrad

Snow, Lucy C.

Kazura, James W.

机构：

[1] Imperial Coll Sch Med, Dept Infect Dis Epidemiol, London W2 1PG, England

[2] Natl Inst Med Res, Dar Es Salaam, Tanzania

[3] Vet Labs Agcy, Ctr Epidemiol & Risk Anal, Addlestone KT15 3NB, Surrey, England

[4] Case Western Reserve Univ, Ctr Global Hlth & Dis, Cleveland, OH 44106 USA

来源：

TRENDS IN PARASITOLOGY | 2006年 / 22卷 / 05期

基金：

美国国家卫生研究院; 英国医学研究理事会;

关键词：

D O I：

10.1016/j.pt.2006.03.005

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The current global initiative to eliminate lymphatic filariasis is a major renewed commitment to reduce or eliminate the burden of one of the major hellminth infections from resource-poor communities of the world. Mathematical models of filariasis transmission can serve as an effective tool for guiding the scientific development and management of successful community-level intervention programmes by acting as analytical frameworks for integrating knowledge regarding parasite transmission dynamics with programmatic factors. However, the power of these tools for supporting control interventions will be realized fully only if researchers address the current uncertainties and gaps in data and knowledge of filarial population dynamics and the effectiveness of currently proposed filariasis intervention options.

引用

页码：226 / 233

页数：8

共 64 条

[51] Annual single-dose diethylcarbamazine plus ivermectin for control of bancroftian filariasis: comparative efficacy with and without vector control [J].