Heterofunctional polymers and core-shell nanoparticles via cascade aminolysis/Michael addition and alkyne-azide click reaction of RAFT polymers

被引：49

作者：

An, Zesheng ^{[1
]}

Tang, Wei ^{[2
]}

Wu, Minghong ^{[1
]}

Jiao, Zheng ^{[1
]}

Stucky, Galen D. ^{[2
]}

机构：

[1] Shanghai Univ, Sch Environm & Chem Engn, Inst Nanochem & Nanobiol, Shanghai 200444, Peoples R China

[2] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

来源：

CHEMICAL COMMUNICATIONS | 2008年 / 48期

关键词：

D O I：

10.1039/b816578e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A convenient methodology involving cascade aminolysis/Michael addition and alkyne-azide click reaction was developed for polymers and polymeric core-shell nanoparticles, synthesized via RAFT-mediated homogeneous and heterogeneous polymerisation processes, respectively, to provide well-defined heterofunctional polymeric materials.

引用

页码：6501 / 6503

页数：3

共 49 条

[1] Facile RAFT precipitation polymerization for the microwave-assisted synthesis of well-defined, double hydrophilic block copolymers and nanostructured hydrogels [J].

An, Zesheng ;

Shi, Qihui ;

Tang, Wei ;

Tsung, Chia-Kuang ;

Hawker, Craig J. ;

Stucky, Galen D. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (46) :14493-14499

[2] Living ring-opening metathesis polymerization [J].

Bielawski, Christopher W. ;

Grubbs, Robert H. .

PROGRESS IN POLYMER SCIENCE, 2007, 32 (01) :1-29

[3] 'Click' chemistry in polymer and material science: An update [J].

Binder, Wolfgang H. ;

Sachsenhofer, Robert .

MACROMOLECULAR RAPID COMMUNICATIONS, 2008, 29 (12-13) :952-981

[4] Direct synthesis of well-defined heterotelechelic polymers for bioconjugations [J].

Boyer, Cyrille ;

Liu, Jingquan ;

Bulmus, Volga ;

Davis, Thomas P. ;

Barner-Kowollik, Christopher ;

Stenzel, Martina H. .

MACROMOLECULES, 2008, 41 (15) :5641-5650

[5] Nanoparticle and targeted systems for cancer therapy [J].

Brannon-Peppas, L ;

Blanchette, JO .

ADVANCED DRUG DELIVERY REVIEWS, 2004, 56 (11) :1649-1659

[6] Living free-radical polymerization by reversible addition-fragmentation chain transfer: The RAFT process [J].

Chiefari, J ;

Chong, YK ;

Ercole, F ;

Krstina, J ;

Jeffery, J ;

Le, TPT ;

Mayadunne, RTA ;

Meijs, GF ;

Moad, CL ;

Moad, G ;

Rizzardo, E ;

Thang, SH .

MACROMOLECULES, 1998, 31 (16) :5559-5562

[7] Temperature-regulated activity of responsive polymer-protein conjugates prepared by grafting-from via RAFT polymerization [J].

De, Priyadarsi ;

Li, Ming ;

Gondi, Sudershan R. ;

Sumerlin, Brent S. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (34) :11288-+

[8] Experimental requirements for an efficient control of free-radical polymerizations via the reversible addition-fragmentation chain transfer (RAFT) process [J].

Favier, Arnaud ;

Charreyre, Marie-Therese .

MACROMOLECULAR RAPID COMMUNICATIONS, 2006, 27 (09) :653-692

[9] Cancer nanotechnology: Opportunities and challenges [J].

Ferrari, M .

NATURE REVIEWS CANCER, 2005, 5 (03) :161-171

[10] Block copolymer micelles: preparation, characterization and application in drug delivery [J].

Gaucher, G ;

Dufresne, MH ;

Sant, VP ;

Kang, N ;

Maysinger, D ;

Leroux, JC .

JOURNAL OF CONTROLLED RELEASE, 2005, 109 (1-3) :169-188

← 1 2 3 4 5 →