Heterogeneous enantioselective hydrogenation of 2-pyrones over cinchona-modified palladium

被引：62

作者：

Huck, WR ^{[1
]}

Mallat, T ^{[1
]}

Baiker, A ^{[1
]}

机构：

[1] ETH Honggerberg, HCI, Swiss Fed Inst Technol, Tech Chem Lab, CH-8093 Zurich, Switzerland

来源：

NEW JOURNAL OF CHEMISTRY | 2002年 / 26卷 / 01期

关键词：

D O I：

10.1039/b108944g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Asymmetric hydrogenation of 4-alkoxy and 4-methyl derivatives of 2-pyrones to the corresponding dihydro- or tetrahydropyrones over cinchona-modified Pd=TiO2 is fast under ambient conditions and affords good yields and high ee. cis-Tetrahydropyrones are obtained with 98-99% de. The ee can be further increased by kinetic resolution.

引用

页码：6 / 8

页数：3

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